Dominic D’Agostino is a professor and inquisitive mind at the University of South Florida’s Morsani College of Medicine. His laboratory works with metabolic-based strategies to combat multiple health problems from epilepsy and seizures, to neurodegenerative diseases, and others.

D’Agostino talks about metabolic therapies. He gives an overview of his thoughts on ketogenic diets and the current data on ketone supplements. He explains that ketosis is a metabolic state that can occur when carbohydrates are removed from one’s diet. Glycogen is depleted and the body is forced to find a new fuel source, thus our bodies can convert fat into ketones for energy. Though the process may be difficult for some to adapt, D’Agostino states that many people who have age-related cognitive issues, inflammation, or even weight problems, can all see improvements and shifts on a ketogenic diet. D’Agostino discusses ketone salts and ketone esters and how they impact the osmotic load inside the gut, and affect general health.

As he explains, ketosis can decrease blood pressure and help combat type II diabetes. D’Agostino delivers information on ketone supplementation and discusses MCTs, or medium-chain triglycerides, in depth. D’Agostino talks about increased cognitive function seen in many who stick to the ketogenic lifestyle, and he underscores how exogenous ketones can play a role in improvement for health even if an individual is not adhering to a strict ketogenic diet.

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